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1.
Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
Nath SR, Yu Z, Gipson TA, Marsh GB, Yoshidome E, Robins DM, Todi SV, Housman DE, Lieberman AP.
J Clin Invest. 2018 May 29. pii: 99042. doi: 10.1172/JCI99042.
2.
Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing.
Gao S, Yan L, Wang R, Li J, Yong J, Zhou X, Wei Y, Wu X, Wang X, Fan X, Yan J, Zhi X, Gao Y, Guo H, Jin X, Wang W, Mao Y, Wang F, Wen L, Fu W, Ge H, Qiao J, Tang F.
Nat Cell Biol. 2018 Jun;20(6):721-734. doi: 10.1038/s41556-018-0105-4. Epub 2018 May 25.
3.
Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.
Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H.
Gut. 2018 May 24. pii: gutjnl-2017-315425. doi: 10.1136/gutjnl-2017-315425.
4.
Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3.
Tanaka K, Martinez GJ, Yan X, Long W, Ichiyama K, Chi X, Kim BS, Reynolds JM, Chung Y, Tanaka S, Liao L, Nakanishi Y, Yoshimura A, Zheng P, Wang X, Tian Q, Xu J, O'Malley BW, Dong C.
Cell Rep. 2018 May 22;23(8):2318-2329. doi: 10.1016/j.celrep.2018.04.088.
5.
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing.
Kim JH, Dilthey AT, Nagaraja R, Lee HS, Koren S, Dudekula D, Wood Iii WH, Piao Y, Ogurtsov AY, Utani K, Noskov VN, Shabalina SA, Schlessinger D, Phillippy AM, Larionov V.
Nucleic Acids Res. 2018 May 21. doi: 10.1093/nar/gky442.
6.
PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM.
Kralovicova J, ?evcikova I, Stejskalova E, Obuca M, Hiller M, Stanek D, Vorechovsky I.
Nucleic Acids Res. 2018 May 18. doi: 10.1093/nar/gky389.
7.
Cooperative binding of ApiAP2 transcription factors is crucial for the expression of virulence genes in Toxoplasma gondii.
Lesage KM, Huot L, Mouveaux T, Courjol F, Saliou JM, Gissot M.
Nucleic Acids Res. 2018 May 21. doi: 10.1093/nar/gky373.
8.
Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.
VanDussen KL, Stojmirovi? A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS.
Gastroenterology. 2018 May 18. pii: S0016-5085(18)34561-X. doi: 10.1053/j.gastro.2018.05.028.
9.
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reynies A, Dusetti N, Iovanna J, Urrutia R.
Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6.
10.
Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.
Page N, Klimek B, De Roo M, Steinbach K, Soldati H, Lemeille S, Wagner I, Kreutzfeldt M, Di Liberto G, Vincenti I, Lingner T, Salinas G, Bruck W, Simons M, Murr R, Kaye J, Zehn D, Pinschewer DD, Merkler D.
Immunity. 2018 May 15;48(5):937-950.e8. doi: 10.1016/j.immuni.2018.04.005.
11.
Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations.
Nguyen Q, Lukowski S, Chiu H, Senabouth A, Bruxner T, Christ A, Palpant N, Powell J.
Genome Res. 2018 May 11. pii: gr.223925.117. doi: 10.1101/gr.223925.117.
12.
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.
Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Lemoine NR, Heeschen C, Castellano L.
Nat Commun. 2018 May 10;9(1):1845. doi: 10.1038/s41467-018-03962-x.
13.
miRNA-590-3p promotes ovarian cancer growth and metastasis via a novel FOXA2-versican pathway.
Salem M, O'Brien JA, Bernaudo S, Shawer H, Ye G, Brki? J, Amleh A, Vanderhyden BC, Refky B, Yang BB, Krylov SN, Peng C.
Cancer Res. 2018 May 10. pii: canres.3014.2017. doi: 10.1158/0008-5472.CAN-17-3014.
14.
Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.
Hauberg ME, Fullard JF, Zhu L, Cohain AT, Giambartolomei C, Misir R, Reach S, Johnson JS, Wang M, Mattheisen M, Børglum AD, Zhang B, Sieberts SK, Peters MA, Domenici E, Schadt EE, Devlin B, Sklar P, Roeder K, Roussos P; CommonMind Consortium.
Mol Psychiatry. 2018 May 8. doi: 10.1038/s41380-018-0059-8.
15.
Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles.
Hawkshaw NJ, Hardman JA, Haslam IS, Shahmalak A, Gilhar A, Lim X, Paus R.
PLoS Biol. 2018 May 8;16(5):e2003705. doi: 10.1371/journal.pbio.2003705. eCollection 2018 May.
16.
Determining the genetic basis of anthracycline-cardiotoxicity by response QTL mapping in induced cardiomyocytes.
Knowles DA, Burrows CK, Blischak JD, Patterson KM, Serie DJ, Norton N, Ober C, Pritchard JK, Gilad Y.
Elife. 2018 May 8;7. pii: e33480. doi: 10.7554/eLife.33480.
17.
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine.
Lei W, Ren W, Ohmoto M, Urban JF Jr, Matsumoto I, Margolskee RF, Jiang P.
Proc Natl Acad Sci U S A. 2018 May 22;115(21):5552-5557. doi: 10.1073/pnas.1720758115. Epub 2018 May 7.
18.
Allele-specific control of replication timing and genome organization during development.
Rivera-Mulia JC, Dimond A, Vera D, Trevilla-Garcia C, Sasaki T, Zimmerman J, Dupont C, Gribnau J, Fraser P, Gilbert DM.
Genome Res. 2018 May 7. doi: 10.1101/gr.232561.117.
19.
Loss of MED12 induces tumor dormancy in human epithelial ovarian cancer via downregulation of EGFR.
Luo XL, Deng C, Su XD, Wang F, Chen Z, Wu XP, Liang SB, Liu J, Fu L.
Cancer Res. 2018 May 7. pii: canres.0134.2018. doi: 10.1158/0008-5472.CAN-18-0134.
20.
SPAR: small RNA-seq portal for analysis of sequencing experiments.
Kuksa PP, Amlie-Wolf A, Katanic ?, Valladares O, Wang LS, Leung YY.
Nucleic Acids Res. 2018 May 4. doi: 10.1093/nar/gky330.
21.
An integrative model for alternative polyadenylation, IntMAP, delineates mTOR-modulated endoplasmic reticulum stress response.
Chang JW, Zhang W, Yeh HS, Park M, Yao C, Shi Y, Kuang R, Yong J.
Nucleic Acids Res. 2018 May 4. doi: 10.1093/nar/gky340.
22.
Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro.
Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH.
Cell Stem Cell. 2018 May 3;22(5):684-697.e9. doi: 10.1016/j.stem.2018.04.009.
23.
Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function.
Shah PT, Stratton JA, Stykel MG, Abbasi S, Sharma S, Mayr KA, Koblinger K, Whelan PJ, Biernaskie J.
Cell. 2018 May 3;173(4):1045-1057.e9. doi: 10.1016/j.cell.2018.03.063.
24.
Transcriptome-wide Interrogation of the Functional Intronome by Spliceosome Profiling.
Chen W, Moore J, Ozadam H, Shulha HP, Rhind N, Weng Z, Moore MJ.
Cell. 2018 May 3;173(4):1031-1044.e13. doi: 10.1016/j.cell.2018.03.062.
25.
Global DNA methylation synergistically regulates the nuclear and mitochondrial genomes in glioblastoma cells.
Sun X, Johnson J, St John JC.
Nucleic Acids Res. 2018 May 2. doi: 10.1093/nar/gky339.
26.
let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration.
Kaur S, Gupta S, Chaudhary M, Khursheed MA, Mitra S, Kurup AJ, Ramachandran R.
Cell Rep. 2018 May 1;23(5):1409-1423. doi: 10.1016/j.celrep.2018.04.002.
27.
The fractured landscape of RNA-seq alignment: the default in our STARs.
Ballouz S, Dobin A, Gingeras TR, Gillis J.
Nucleic Acids Res. 2018 May 1. doi: 10.1093/nar/gky325.
28.
The arginine methyltransferase CARM1 represses p300?ACT?CREMτ activity and is required for spermiogenesis.
Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford MT.
Nucleic Acids Res. 2018 May 18;46(9):4327-4343. doi: 10.1093/nar/gky240.
29.
SEASTAR: systematic evaluation of alternative transcription start sites in RNA.
Qin Z, Stoilov P, Zhang X, Xing Y.
Nucleic Acids Res. 2018 May 4;46(8):e45. doi: 10.1093/nar/gky053.
30.
Hierarchical interactions between Fnr orthologs allows fine-tuning of transcription in response to oxygen in Herbaspirillum seropedicae.
Batista MB, Chandra G, Monteiro RA, de Souza EM, Dixon R.
Nucleic Acids Res. 2018 May 4;46(8):3953-3966. doi: 10.1093/nar/gky142.
31.
A regulatory RNA is involved in RNA duplex formation and biofilm regulation in Sulfolobus acidocaldarius.
Orell A, Tripp V, Aliaga-Tobar V, Albers SV, Maracaja-Coutinho V, Randau L.
Nucleic Acids Res. 2018 May 18;46(9):4794-4806. doi: 10.1093/nar/gky144.
32.
CXCL1-CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration.
Wang L, Zhang YL, Lin QY, Liu Y, Guan XM, Ma XL, Cao HJ, Liu Y, Bai J, Xia YL, Du J, Li HH.
Eur Heart J. 2018 May 21;39(20):1818-1831. doi: 10.1093/eurheartj/ehy085.
33.
Improving the value of public RNA-seq expression data by phenotype prediction.
Ellis SE, Collado-Torres L, Jaffe A, Leek JT.
Nucleic Acids Res. 2018 May 18;46(9):e54. doi: 10.1093/nar/gky102.
34.
Octopus-toolkit: a workflow to automate mining of public epigenomic and transcriptomic next-generation sequencing data.
Kim T, Seo HD, Hennighausen L, Lee D, Kang K.
Nucleic Acids Res. 2018 May 18;46(9):e53. doi: 10.1093/nar/gky083.
35.
RNentropy: an entropy-based tool for the detection of significant variation of gene expression across multiple RNA-Seq experiments.
Zambelli F, Mastropasqua F, Picardi E, D'Erchia AM, Pesole G, Pavesi G.
Nucleic Acids Res. 2018 May 4;46(8):e46. doi: 10.1093/nar/gky055.
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